Wait, what? Square's making a game that isn't a shitty RPG that's basically the same game they've been making for about a decade(and im not even counting the games that are the same games!)?! Remarkable. I can't say that I've been excited about any SE games lately, except for Dragon Quest IX that is(not counting Chrono Trigger, and Dragon Quest IV, because I already liked those), but NnG is definitely something I could get fired up about. That is, if they bother to release the damned thing in NA.
Unless the game is way too Japano-centric for western audiences, I see no reason why they should refrain from bringing it over here. In fact, being Japano-centric probably wouldn't hinder their sales much, if at all. Does it even specifically take place in Japan? Probably, but it doesn't matter, as long as it isn't filled to the brim with japfag-orgasm-inducing-Jpop shit and the like(that's like, one of the main reason I didn't pick up The World Ends With You).
I'd take this over the next FF, Kingdom Hearts, or game that's not in either of those franchises, but might as well be since it's basically the same thing, any day.