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Mine is very cliche, but I say Mitch Hedberg, and George Carlin. Mitch has the best delivery and style ever, and George Carlin is just hilarious and intelligent at the same time.
I got to agree with Hedberg. He is one that will be missed dearly.
Mel Brooks, Cleavon Little, Gene Wilder, Steve Oedekerk, Stephen Chow, Dave Chapelle.
I'd definitely need to agree with might be a couch about Demetri Martin, the guy is a riot. I wouldn't go as far as to say he is a genius or anything, because I'm somewhat convinced that a good majority of his jokes are drug induced. i.e., his "where his jokes come from" sketch. o.O; Seriously. I'm also jumping on the Mitch Hedberg bandwagon.
Dane Cook is ok, but it seems like he tries a little too hard to be crazy funny, and he's really not all that original. Ike Barinholtz was able to impresonate his act just about perfectly on MadTV. (<3) http://www.youtube.com/watch?v=Zy4zgCsgqyo