I used to like Family Guy, but not anymore. I liked them when they played the first episodes on FOX, yet when I watch the newer ones....it's like they aren't even trying anymore. Even Stewie is losing his charm.
On a side note, I love South Park. It seems to capture more current events then Family Guy, and some of the jokes are geniunly funny. Plus, most of the characters aren't even that bad (Only characters I hate are Wendy and Pip). On the negative side, sometimes the humor is simply tasteless and bland.
In the end, Futurama is much more interesting. :p