No, probably not. He has good ratings, but it's a second-tier show on a cable network and he's only campaigning in one state, without presenting strong platforms.
It's hilarious, and awesome, yes, but will he win? Would he even get 10% of the popular vote? Not a chance. Just because a good majority of people on this board know who he is, that's not a good demographic statistic on all of the U.S., many of which don't even have cable.
What's important is that he'd take a percentage (even just a small one) away from a party in the biggest swing state in the country after Ohio, and that could affect the polls in interesting ways.